Pasta News Network - New Zealand

A 17-year-old male presented with COVID-19 vaccine-associated myocarditis. Six months later, due to chest discomfort with exercise, the patient underwent an exercise stress test that revealed a 3-beat run of nonsustained ventricular tachycardia at 230 bpm at peak exercise. The long-term outcomes of COVID-19 vaccine-associated myocarditis are unclear. This patient had nonsustained ventricular tachycardia over 6 months after diagnosis.

See Figure 1, the little white arrow, is pointing at scar tissue.

Interpretation: Although rare, a statistically significant association between BNT162b2 vaccination and myo/pericarditis and AKI was observed. While the association between BNT162b2 and myo/pericarditis has been confirmed internationally, further research is required to understand the association of AKI. BNT162b2 was not found to be associated with most of the AESIs investigated, providing reassurances around the safety of the vaccine.

Page 5:

The safety of BNT162b2 is monitored predominantly through a spontaneous reporting (passive) system by Medsafe, in collaboration with the Centre for Adverse Reactions Monitoring (CARM), with support from the COVID-19 Vaccine and Immunisation Programme within the Ministry of Health New Zealand. This system relies on reports being voluntarily submitted by health care professionals and the public. Although it is effective at signal detection, it can be subject to several limitations, namely underreporting, incomplete reports, limited information on cases and reporting biases.

Remember that in Medsafe's own words "it is estimated that only 5% of all reactions are reported so there is still room for improvement."

Page 12:

These findings provide further reassurance on the safety profile of the vaccine, particularly from a New Zealand specific context. Importantly, studies have found that the risk of any of these AESI following SARS-CoV-2 infection is substantially greater than after COVID-19 mRNA vaccination.

There it is.

Also, they only looked at 21 days post vaccination when there have been multiple signals there can be problem 60 days out.

With regard to medical and pharmacological research projects, I.G. Farben became involved in experimental programmes using patients from the Nazi regime’s euthanasia programmes and healthy subjects recruited without their consent from concentration camps, on whom various pharmacological substances were tested, including sulfamide and arsenical derivatives and other preparations whose composition is not precisely known (B-1012, B-1034, 3382 or Rutenol, 3582 or Acridine), generally in relation to the treatment of infectious diseases, such as typhus, erysipelas, scarlet fever or paratyphoid diarrhoea.

Furthermore, I.G. Farben played a decisive role in the German army’s chemical warfare programme, contributing to the development of the first two neurotoxic substances, later known as ‘nerve agents’, tabun and sarin.

Some of these activities came to light as a result of the one the famous Nuremberg Trials in 1947, which saw 24 executives and scientists from I.G. Farben brought to justice for, among other offences, the use of slave labour in the concentration camps and forced experimentation with drugs on prisoners.

Ivermectin is an anti-parasitic agent that has gained attention as a potential COVID-19 therapeutic. It is a compound of the type Avermectin, which is a fermented by-product of Streptomyces avermitilis. Bifidobacterium is a member of the same phylum as Streptomyces spp., suggesting it may have a symbiotic relation with Streptomyces. Decreased Bifidobacterium levels are observed in COVID-19 susceptibility states, including old age, autoimmune disorder, and obesity. We hypothesize that Ivermectin, as a by-product of Streptomyces fermentation, is capable of feeding Bifidobacterium, thereby possibly preventing against COVID-19 susceptibilities. Moreover, Bifidobacterium may be capable of boosting natural immunity, offering more direct COVID-19 protection. These data concord with our study, as well as others, that show Ivermectin protects against COVID-19.

One of the few papers that links Ivermectin with gut biome health.

From what I've learned so-far, a happy gut biome is very advantageous to the immune system.

By December 2022, the BA.4 strain was no longer circulating, and BA.5 accounted for less than 25% of circulating SARS-CoV-2 strains, having been partially replaced by more immune-evasive strains, such as BQ.1, BQ.1.1, BF.7, XBB, and XBB.1.

What lessons can be learned from our experience with bivalent vaccines?

Fortunately, SARS-CoV-2 variants haven’t evolved to resist the protection against severe disease offered by vaccination or previous infection. If that happens, we will need to create a variant-specific vaccine. Although boosting with a bivalent vaccine is likely to have a similar effect as boosting with a monovalent vaccine, booster dosing is probably best reserved for the people most likely to need protection against severe disease — specifically, older adults, people with multiple coexisting conditions that put them at high risk for serious illness, and those who are immunocompromised. In the meantime, I believe we should stop trying to prevent all symptomatic infections in healthy, young people by boosting them with vaccines containing mRNA from strains that might disappear a few months later.

As penned by Paul A. Offit, M.D., CDC panel member.

Vitamin C, also known as ascorbic acid, is used as a supplement for fighting infectious disorders. Many disorders, including COVID-19 and cancer, harmfully disrupt the levels of bacteria that naturally reside in the gut, which may contribute to symptoms. The aim of the study was to understand whether high-dose vitamin C could improve the types of bacteria in the human gut. To do this we characterized the gut bacteria before and after 23 individuals took vitamin C, as prescribed by their respective physicians. We observed that vitamin C increased levels of a gut bacterium called Bifidobacterium which has positive health benefits, including fighting infection. This study suggests the possibility that vitamin C could be successful for improving infection outcomes, possibly even COVID-19, partially because it improves the gut bacteria present.

To acompany Sabine Hazan's Ivermectin paper.

You get through at least a kilogram of raw carrots every day; the whites of your eyes and your skin have turned yellow; and you panic if you discover that your carrot supply has dried up. If you recognise these symptoms, you are probably addicted to raw carrots. It's rare but it does occur. A Czech psychiatrist described three cases some decades ago.

Two Papers, Three case studies, with references. One titled "The Orange People".

By December 2022, the BA.4 strain was no longer circulating, and BA.5 accounted for less than 25% of circulating SARS-CoV-2 strains, having been partially replaced by more immune-evasive strains, such as BQ.1, BQ.1.1, BF.7, XBB, and XBB.1.

What lessons can be learned from our experience with bivalent vaccines?

Fortunately, SARS-CoV-2 variants haven’t evolved to resist the protection against severe disease offered by vaccination or previous infection. If that happens, we will need to create a variant-specific vaccine. Although boosting with a bivalent vaccine is likely to have a similar effect as boosting with a monovalent vaccine, booster dosing is probably best reserved for the people most likely to need protection against severe disease — specifically, older adults, people with multiple coexisting conditions that put them at high risk for serious illness, and those who are immunocompromised. In the meantime, I believe we should stop trying to prevent all symptomatic infections in healthy, young people by boosting them with vaccines containing mRNA from strains that might disappear a few months later.

As penned by Paul A. Offit, M.D., CDC panel member.

From 2015:

It is therefore unfortunate that Cochrane reviews seems systematically to conflict with the information and recommendations from the World Health Organization (WHO). A number of the drugs and vaccines recommended by WHO, especially the drugs used in psychiatry, are in Cochrane reviews found to be harmful and without significant clinical effect. Since whose recommendations are followed by many people in the member states, it could indeed lead to patients getting the wrong medication and many patients have severe adverse effects, because of these drugs. To solve this serious public health problem it is recommended to revise the WHO-system, which in fact has been proven weak to the interests of the pharmaceutical industry. We therefore believe that the WHO’s recommendations regarding medicine in its “list of essential medicines” and other drug directories are biased and not reliable as a source of information on medicine

The money shot:

The World Health Organization (WHO) is guiding the public health services of 194 member states and a number of other countries regarding their use of pharmacological drugs, vaccines, and non-drug medicine (psychotherapy, physical therapy, alternative medicine(CAM) etc.). Ten years ago WHO changed its financial policy and allowed private money into its system, instead of only funding from the member states. WHO has since been extremely successful in raising funds and is now receiving more than half of its yearly budget from private sources. Bill Gates has for example given more than one billion dollars to the WHO. The new system of private funding of WHO has brought WHO much closer to the pharmaceutical industry.

The repetitive applications of vaccine boosters have been brought up in face of continuous emergence of SARS-CoV-2 variants with neutralization escape mutations, but their protective efficacy and potential adverse effects remain largely unknown. Here, we compared the humoral and cellular immune responses of an extended course of recombinant receptor binding domain (RBD) vaccine boosters with those from conventional immunization strategy in a Balb/c mice model. Multiple vaccine boosters after the conventional vaccination course significantly decreased RBD-specific antibody titers and serum neutralizing efficacy against the Delta and Omicron variants, and profoundly impaired CD4+ and CD8+T cell activation and increased PD-1 and LAG-3 expressions in these T cells. Mechanistically, we confirmed that extended vaccination with RBD boosters overturned the protective immune memories by promoting adaptive immune tolerance. Our findings demonstrate potential risks with the continuous use of SARS-CoV-2 vaccine boosters, providing immediate implications for the global COVID-19 vaccination enhancement strategies.

Interesting to note how Asian science teams are far more pro-active in this type of research then Western ones are.

Ticks the boxes, CD4, CD8, PD-1.

Lightning discharges between charged clouds and the Earth’s surface are responsible for considerable damages and casualties. It is therefore important to develop better protection methods in addition to the traditional Franklin rod. Here we present the first demonstration that laser-induced filaments—formed in the sky by short and intense laser pulses—can guide lightning discharges over considerable distances. We believe that this experimental breakthrough will lead to progress in lightning protection and lightning physics. An experimental campaign was conducted on the Säntis mountain in north-eastern Switzerland during the summer of 2021 with a high-repetition-rate terawatt laser.

The guiding of an upward negative lightning leader over a distance of 50 m was recorded by two separate high-speed cameras. The guiding of negative lightning leaders by laser filaments was corroborated in three other instances by very-high-frequency interferometric measurements, and the number of X-ray bursts detected during guided lightning events greatly increased. Although this research field has been very active for more than 20 years, this is the first field-result that experimentally demonstrates lightning guided by lasers. This work paves the way for new atmospheric applications of ultrashort lasers and represents an important step forward in the development of a laser based lightning protection for airports, launchpads or large infrastructures.

Figure 1 looks bad ass.

Background: Concerns have been raised recently regarding the efficacy and safety of Botulinum toxin type A (BTA) injections following COVID-19 vaccination.

Results: Forty-five patients were eligible for inclusion in the current study. The mean (standard deviation [SD]) age of patients was 48.3 (8.9) years and 40 (88.9%) patients were females. The mean (SD) number of pre- and post-COVID-19 vaccination BTA injections was 5.1 (2.6) and 3.1 (0.4), respectively. The average (SD) interval between BTA injections after COVID-19 vaccination (96.0 [12.3] days) was significantly shorter than before it (118.6 [22.7]; p < 0.001). No severe BTA-associated adverse events were registered after the administration of BNT162b2 vaccine.

Conclusions: Our findings indicate that BTA might be less effective after COVID-19 vaccination. Further research is required to delineate the pathomechanism underlying this observation.

How does an inoculation product interfere with a beautification product...

Hat tip to the Hatchard Report from the other day.

Summary: Among 51011 working-aged Cleveland Clinic employees, the bivalent COVID-19 vaccine booster was 30% effective in preventing infection, during the time when the virus strains dominant in the community were represented in the vaccine.

See Figure 2. The more you have been jabbed, the higher risk you are at catching covid.

It reads very much like "we have to say the right things else we do not get published", ergo:

In conclusion, this study found an overall modest protective effect of the bivalent vaccine booster against COVID-19, among working-aged adults. The effect of multiple COVID-19 vaccine doses on future risk of COVID-19 needs further study.

Question: Are COVID-19 vaccines associated with increased risk of thromboembolic and thrombocytopenic events?

Conclusions and Relevance: In this self-controlled case series, there was an increased rate of hospital contacts because of coagulation disorders and cerebrovascular disease, especially for thrombocytopenia and cerebral venous thrombosis, following vaccination with AZD1222. Although increased rates of several thromboembolic and thrombocytopenic outcomes following BNT162b2 and mRNA-1273 vaccination were observed, these increases were less than the rates observed after AZD1222, and sensitivity analyses were not consistent. Confirmatory analysis on the 2 mRNA vaccines by other methods are warranted.

Results: Instead, the mRNA, but not the adenovirus-based vaccines induced long-term IgG4 responses – the IgG subclass with inhibitory effector functions. Furthermore, salivary anti-S IgA levels were lower and decreased faster in naïve as compared to pre-infected vaccinees.

Conclusion: In summary, the study suggests a comparable “adjuvant” potential of the newly developed vaccines on the anti-S IgG Fc glycosylation, as reflected in relatively low long-term anti-S IgG1 galactosylation levels generated by the long-lived plasma cell pool, whose induction might be driven by a recently described TH1-driven B cell response for all three vaccines. Instead, repeated immunization of naïve individuals with the mRNA vaccines increased the proportion of the IgG4 subclass over time which might influence the long-term Ab effector functions. Taken together, these data shed light on these novel vaccine formats and might have potential implications for their long-term efficacy.

See Figure 2.

There are some really weird outliers in the data.

• One, is likely the difference in immune respones between humans.
• Two, another possible confirmation of "hot lots"?

People becoming tolerant to spike protein would be Very Bad™

From 2005:

“Journals have devolved into information laundering operations for the pharmaceutical industry”, wrote Richard Horton, editor of the Lancet, in March 2004. In the same year, Marcia Angell, former editor of the New England Journal of Medicine, lambasted the industry for becoming “primarily a marketing machine” and co-opting “every institution that might stand in its way”. Medical journals were conspicuously absent from her list of co-opted institutions, but she and Horton are not the only editors who have become increasingly queasy about the power and influence of the industry. Jerry Kassirer, another former editor of the New England Journal of Medicine, argues that the industry has deflected the moral compasses of many physicians , and the editors of PLoS Medicine have declared that they will not become “part of the cycle of dependency…between journals and the pharmaceutical industry”. Something is clearly up.

That was 18 years ago, I would say things have only gotten more... Awkward. Short and honest.

Cases of myocarditis, diagnosed clinically by laboratory tests and imaging have been described in the context of mRNA-based anti-SARS-CoV-2 vaccination. Autopsy-based description of detailed histological features of vaccine-induced myocarditis is lacking. We describe the autopsy findings and common characteristics of myocarditis in untreated persons who received anti-SARS-CoV-2 vaccination. Standardized autopsies were performed on 25 persons who had died unexpectedly and within 20 days after anti-SARS-CoV-2 vaccination. In four patients who received a mRNA vaccination, we identified acute (epi-)myocarditis without detection of another significant disease or health constellation that may have caused an unexpected death.

Figures 1, 2 and 3. Essentially, all those off-colour dots are not meant to be there.

Viruses impact host cells and have indirect effects on ecosystem processes. Plankton such as ciliates can reduce the abundance of virions in water, but whether virus consumption translates into demographic consequences for the grazers is unknown. Here, we show that small protists not only can consume viruses they also can grow and divide given only viruses to eat. Moreover, the ciliate Halteria sp. foraging on chloroviruses displays dynamics and interaction parameters that are similar to other microbial trophic interactions. These results suggest that the effect of viruses on ecosystems extends beyond (and in contrast to) the viral shunt by redirecting energy up food chains.

Nature will recycle anything.

From 2020:

The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness, hospitalizations, and death. The complex and multifaceted pathophysiology of life-threatening COVID-19 illness including viral mediated organ damage, cytokine storm, and thrombosis warrants early interventions to address all components of the devastating illness. In countries where therapeutic nihilism is prevalent, patients endure escalating symptoms and without early treatment can succumb to delayed in-hospital care and death. Prompt early initiation of sequenced multidrug therapy (SMDT) is a widely and currently available solution to stem the tide of hospitalizations and death.

Genuinely "Safe & Effective". Early treatment could have been, and can still be, done cheap.

• Hydroxychloroquine (HCQ)
• Ivermectin (IVM)
• Zinc
• Vitamin C
• Vitamin D

Don't forget to exercise for beneficial cytokine storms that strengthen the immune system.

Despite its well-known association with IgE-mediated allergy, IgG4 antibodies still have several poorly understood characteristics. IgG4 is a very dynamic antibody: the antibody is involved in a continuous process of half-molecules (i.e. a heavy and attached light-chain) exchange. This process, also referred to as ‘Fab-arm exchange’, results usually in asymmetric antibodies with two different antigen-combining sites. While these antibodies are hetero- bivalent, they will behave as monovalent antibodies in most situations. Another aspect of IgG4, still poorly understood, is its tendency to mimic IgG rheumatoid factor (RF) activity by interacting with IgG on a solid support. In contrast to conventional RF, which binds via its variable domains, the activity of IgG4 is located in its constant domains.

Beekeepers are exposed to multiple stings in season although they are immune to the effects apart from local swellings at the site of the sting. This is in contrast to venom-allergic individuals who are in general stung only occasionally yet remain at risk of IgE-mediated anaphylaxis. To assess the mechanism of tolerance in beekeepers, we measured their serum allergen-specific IgE and IgG4 levels. We measured the ability of their serum to form bee venom IgE-allergen complexes (the IgE-facilitated-allergen binding [FAB] assay).

The immune system is a magical thing.

Shortly after the initial two mRNA vaccine doses, the IgG response mainly consists of the pro-inflammatory subclasses IgG1 and IgG3. Here, we report that several months after the second vaccination, SARS-CoV-2-specific antibodies were increasingly composed of non-inflammatory IgG4, which were further boosted by a third mRNA vaccination and/or SARS-CoV-2 variant breakthrough infections. IgG4 antibodies among all spike-specific IgG antibodies rose on average from 0.04% shortly after the second vaccination to 19.27% late after the third vaccination. This induction of IgG4 antibodies was not observed after homologous or heterologous SARS-CoV-2 vaccination with adenoviral vectors.

This is not Good.

Importantly, this class switch was associated with a reduced capacity of the spike-specific antibodies to mediate antibody-dependent cellular phagocytosis and complement deposition. Since Fc-mediated effector functions are critical for antiviral immunity, these findings may have consequences for the choice and timing of vaccination regimens using mRNA vaccines, including future booster immunizations against SARS-CoV-2.

This would imply, that the anti-body overload the mRNA vaccines ellicit may turn a segment of the populace into perpetual "plague rats".

During the Weimar Republic in the mid-twentieth century, more than half of all German physicians became early joiners of the Nazi Party, surpassing the party enrollments of all other professions. From early on, the German Medical Society played the most instrumental role in the Nazi medical program, beginning with the marginalization of Jewish physicians, proceeding to coerced “experimentation,” “euthanization,” and sterilization, and culminating in genocide via the medicalization of mass murder of Jews and others caricatured and demonized by Nazi ideology.

Given the medical oath to “do no harm,” many postwar ethical analyses have strained to make sense of these seemingly paradoxical atrocities. Why did physicians act in such a manner?

Social Peer Pressure, one hell of a drug.

The evolution of the human diet over the past 10,000 years from a Paleolithic diet to our current modern pattern of intake has resulted in profound changes in feeding behavior. Shifts have occurred from diets high in fruits, vegetables, lean meats, and seafood to processed foods high in sodium and hydrogenated fats and low in fiber.

This is fine.

Rapid recognition of SARS-CoV-2–infected cells by resident T cells in the upper airway might provide an important layer of protection against COVID-19. Whether parenteral SARS-CoV-2 vaccination or infection induces nasal-resident T cells specific for distinct SARS-CoV-2 proteins is unknown. We isolated T cells from the nasal mucosa of COVID-19 vaccinees who either experienced SARS-CoV-2 infection after vaccination (n = 34) or not (n = 16) and analyzed their phenotype, SARS-CoV-2 specificity, function, and persistence.

Natural immunity is best immunity.

The COVID-19 period highlights a huge problem that has been developing for decades, the control of science by industry. In the 1950s, the tobacco industry set the example, which the pharmaceutical industry followed. Since then, the latter has been regularly condemned for illegal marketing, misrepresentation of experimental results, dissimulation of information about the dangers of drugs, and considered as criminal. Therefore, this study was conducted to show that knowledge is powerfully manipulated by harmful corporations, whose goals are = 1/financial; 2/to suppress our ability to make choices to acquire global control of public health.

I am Jack's complete lack of surprise.

Effective diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines became available in the 1930s, and they were put into routine use in the United States in the 1940s. Their use reduced the average rate of reported pertussis cases from 157 in 100 000 in the prevaccine era to <1 in 100 000 in the 1970s. Because of alleged reactions (encephalopathy and death), several countries discontinued (Sweden) or markedly decreased (United Kingdom, Germany, Japan) use of the vaccine.

Abstract Ending

Because of the small number of antigens (3–5 in DTaP vaccines vs >3000 in DTwP vaccines), linked-epitope suppression occurs. Because of linked-epitope suppression, all children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes, and there is no easy way to decrease this increased lifetime susceptibility.

From 2019:

Question: Is the use of N95 respirators or medical masks more effective in preventing influenza infection among outpatient health care personnel in close contact with patients with suspected respiratory illness?

Findings: In this pragmatic, cluster randomized clinical trial involving 2862 health care personnel, there was no significant difference in the incidence of laboratory-confirmed influenza among health care personnel with the use of N95 respirators (8.2%) vs medical masks (7.2%).

Meaning: As worn by health care personnel in this trial, use of N95 respirators, compared with medical masks, in the outpatient setting resulted in no significant difference in the rates of laboratory-confirmed influenza.

Conclusions and Relevance: Among outpatient health care personnel, N95 respirators vs medical masks as worn by participants in this trial resulted in no significant difference in the incidence of laboratory-confirmed influenza.

Influenza and Covid share similar rules in regards to their particle size if I remember correctly, so make of this what you will.

Realistically to avoid both you need a P100 mask / ventilator.

From 2020:

Results: The workflow reliably detects 2019-nCoV, and further discriminates 2019-nCoV from SARS-CoV. Through coordination between academic and public laboratories, we confirmed assay exclusivity based on 297 original clinical specimens containing a full spectrum of human respiratory viruses. Control material is made available through European Virus Archive – Global (EVAg), a European Union infrastructure project.

Conclusion: The present study demonstrates the enormous response capacity achieved through coordination of academic and public laboratories in national and European research networks.

Consensus, based on copy shown on various lab websites, to be that a normal PCR process is anywhere from 20 - 30 cycles. Going past 35 risks false positives. The workflow recommends a PCR process with 45 cycles.

If you want a casedemic, this is one way to do it.

From 2011:

Fibrin is the main structural component of the thrombus. The conversion of fibrinogen to fibrin by thrombin leads to one of the most remarkable processes in biology in which fibrin spontaneously forms a gel by producing fibers that grow longitudinally as well as laterally, with branch points forming and interconnecting the fibers leading to the formation of a 3-dimensional network that binds platelets and traps other blood cells. Even after the gel point, the architecture of the fibrin network can change quite dramatically.

Something to keep in mind as some papers have discussed how spike protein may dis-regulate fibrin behaviour as well as causing damage to the endothelium.

Intro: Research has demonstrated the association between vaginal orgasm and better mental health. Some theories of psychotherapy assert a link between muscle blocks and disturbances of both character and sexual function. In Functional–Sexological therapy, one focus of treatment is amelioration of voluntary movement. The present study examines the association of general everyday body movement with history of vaginal orgasm.

Conclusion: The discerning observer may infer women's experience of vaginal orgasm from a gait that comprises fluidity, energy, sensuality, freedom, and absence of both flaccid and locked muscles. Results are discussed with regard to previous research on gait, the effect of the musculature on sexual function, the special nature of vaginal orgasm, and implications for sexual therapy.

The curious kind of science.

Many species synchronize reproductive behavior with a particular phase of the lunar cycle to increase reproductive success. In humans, a lunar influence on reproductive behavior remains controversial, although the human menstrual cycle has a period close to that of the lunar cycle. Here, we analyzed long-term menstrual recordings of individual women with distinct methods for biological rhythm analysis. We show that women’s menstrual cycles with a period longer than 27 days were intermittently synchronous with the Moon’s luminance and/or gravimetric cycles. With age and upon exposure to artificial nocturnal light, menstrual cycles shortened and lost this synchrony. We hypothesize that in ancient times, human reproductive behavior was synchronous with the Moon but that our modern lifestyles have changed reproductive physiology and behavior.

I was reminded of this when I prepared the other paper's post today.

The emphasis on a false climate crisis is becoming a tragedy for modern civilization, which depends on relible, economic, and environmentally viable energy. The windmills, solar panels and backup batteries have none if these qualities. This falsehood is pushed by a powerful lobby which Bjorn Lomborg has called a climate industrial complex, comprising some scientists, most media, industrialists, and legislators. It has somehow managed to convince many that CO2 in the atmosphere, a gas necessary for life on earth, one which we exhale with every breath, is an environmental poison. Multiple scientific theories and measurements show that there is no climate crisis. Radiation forcing calculations by both skeptics and believers show that the carbon dioxide radiation forcicng is about 0.3% of the incident radiation, far less than other effects on climate. Over the period of human civilization, the temperature has oscillated between quite a few warm and cold periods, with many of the warm periods being warmer than today. During geological times, it and the carbon dioxide level have been all over the place with no correlation between them.

"We should not be surprised or impressed that those who stand to make a profit are among the loudest calling for politicians to act."

17 pages with graphs. Pro-nuclear stance which I would be inclined to agree with given the other current available alternatives to coal / oil / gas.

Worth reading in full, as referenced by today's Daily Sceptic article.

From 2021:

A previously symptomless 86-year-old man received the first dose of the BNT162b2 mRNA COVID-19 vaccine. He died 4 weeks later from acute renal and respiratory failure. Although he did not present with any COVID-19-specific symptoms, he tested positive for SARS-CoV-2 before he died. Spike protein (S1) antigen-binding showed significant levels for immunoglobulin (Ig) G, while nucleocapsid IgG/IgM was not elicited. Acute bronchopneumonia and tubular failure were assigned as the cause of death at autopsy; however, we did not observe any characteristic morphological features of COVID-19. Postmortem molecular mapping by real-time polymerase chain reaction revealed relevant SARS-CoV-2 cycle threshold values in all organs examined (oropharynx, olfactory mucosa, trachea, lungs, heart, kidney and cerebrum) except for the liver and olfactory bulb. These results might suggest that the first vaccination induces immunogenicity but not sterile immunity.

Figure 1 is worth a gander.

Inquiring minds have questions.

We also find that after controlling for vitamin D blood levels, veterans receiving higher dosages of Vitamin D obtained greater benefits from supplementation than veterans receiving lower dosages. Veterans with Vitamin D blood levels between 0 and 19 ng/ml exhibited the largest decrease in COVID-19 infection following supplementation. Black veterans received greater associated COVID-19 risk reductions with supplementation than White veterans. As a safe, widely available, and affordable treatment, Vitamin D may help to reduce the severity of the COVID-19 pandemic.

The money shot:

When we extrapolate our results for vitamin D3 supplementation to the entire US population in 2020, there would have been approximately 4 million fewer COVID-19 cases and 116,000 deaths avoided

Black individuals have been found to report the highest levels of self-esteem of any racial group in the United States. The purpose of the present research was to examine whether Black individuals also report higher levels of narcissism than White individuals. Study 1 (N = 367) found that Black individuals reported higher levels of narcissism than White individuals even when controlling for gender, self-esteem level, and socially desirable response tendencies. Study 2 (N = 967) and Study 3 (N = 315) found similar results such that Black individuals reported higher levels of narcissism than White individuals on the narcissism measures that captured less pathological facets of this construct.

Study 3 also included indicators of psychological adjustment and found that the pathological aspects of narcissism were more strongly associated with maladjustment for Black individuals than for White individuals. The implications of these results for understanding the Black self-esteem advantage are discussed.

Black males also have higher levels of estrogen compared to their white counterparts, which may account for stronger emotional responses and coping mechanisms.

Context: Higher testosterone in black compared with white men has been postulated to explain their higher prostate cancer incidence. Previous studies comparing hormone levels by race might have been limited by size, restricted age variation, or lack of representation of the general population.

Conclusions: Contrary to the postulated racial difference, testosterone concentrations did not differ notably between black and white men. However, blacks had higher estradiol levels. Mexican-Americans had higher testosterone than whites but similar estradiol and SHBG concentrations. Given these findings, it may be equally if not more important to investigate estradiol as testosterone in relation to diseases with racial disparity.

Reference for the other paper posted today.

As rates of infection with influenza and RSV rose in fall/winter 2022, FLCCC adapted the I-PREVENT protocol to include prevention against these viruses. The interventions recommended are likely to reduce the risk and severity of infection with COVID-19, influenza, and RSV infections as well as the common cold. It should be noted that the medications included in the I-PREVENT protocol are inexpensive, safe, and widely available. This protocol includes a section for pre-exposure (long-term) as well as a post-exposure (acute, short-term)

Not a paper, but certainly helpful.

Linking as the FLCCC protocols have received an update again.

Also checkout their I-CARE and MATH+ protocols on the same page.

For those not familiar, the FLCCC is an amazing group of people that realised "early treatment" is the key in fighting Covid.

In stark contrast to, "Stay home till your face turns blue. Then come to the hospital for help." as was espoused in the majoirty of Western countries at the height of the pandemic.

In 2016, Utah became the first state to pass a resolution declaring pornography a public health crisis. All subsequent states have introduced resolutions using similar or identical language. Resolution language originated from theologically conservative Christian advocacy groups, not from public health agencies. Generally, the resolutions declare that pornography leads to risky sexual behavior, affects brain development and functioning, is potentially addictive, and increases infidelity. Further, they declare that pornography normalizes violence, which leads to increases in sex trafficking, prostitution, childhood sexual abuse, and child pornography. Some of these contentions are supported by research, others are partially supported, and some are unsupported.

Yes.

Pornography does not directly or imminently lead to death, infectious disease morbidity, property destruction, or population displacement.

And, yes.

Depending on the overall magnitude and quality of the memory response and the incubation period of the pathogen, it can be eliminated prior to the establishment of the infection. Elimination of the pathogen even before it can infect a host cell and replicate, ideally directly at the site of entry, is referred to as sterilizing immunity (see Box 1 for glossary of terms). Antibodies are the main mediators of sterilizing immunity, but T cells may contribute to the elimination of infected host cells before the pathogen starts to replicate. By definition, sterilizing immunity prevents pathogen transmission.

The money shot:

Strong humoral responses in the upper respiratory tract might be necessary for protection from the infection at the site of virus entry, but potent mucosal immunity is not easy to achieve by vaccination.

A vaccine injected into the deltoid, that only stimulates a spike (S) protein response and not spike (S) + nucleocapsid (N) as would a natural infection, is not going to help there either.

A very accessible paper worth sharing.

All-cause mortality by week in Australia shows that there was no detectable excess mortality 13 months into the declared pandemic, followed by a step-wise increase in mortality in mid-April 2021, synchronous with the rollout of the COVID-19 vaccine prioritizing elderly, disabled and aboriginal residents.

The excess mortality in the vaccination period (mid-April 2021 through August 2022; 14% larger all-cause mortality than in recent pre-vaccination periods of same time duration; 62 million administered vaccine doses) was 31±1 thousand deaths, which is more than twice the deaths registered as from or with COVID-19.

In addition, a sharp peak in all-cause mortality (mid-January to mid-February 2022; 2,600 deaths) is synchronous with the rapid rollout of the booster (9.4 million booster doses, same time period), and is not due to a climatic heatwave.

Excess mortality in Australia is causally associated with the COVID-19 vaccine. The corresponding vaccine injection fatality ratio (vIFR) is approximately 0.05%.

Awkward.

• Across 31 systematically identified national seroprevalence studies in the pre-vaccination era, the median infection fatality rate of COVID-19 was estimated to be 0.034% for people aged 0–59 years people and 0.095% for those aged 0–69 years.

• The median IFR was 0.0003% at 0–19 years, 0.002% at 20–29 years, 0.011% at 30–39 years, 0.035% at 40–49 years, 0.123% at 50–59 years, and 0.506% at 60–69 years.

• At a global level, pre-vaccination IFR may have been as low as 0.03% and 0.07% for 0–59 and 0–69 year old people, respectively.

• These IFR estimates in non-elderly populations are lower than previous calculations had suggested.

Wikipedia indicates that Influenza has an IFR < 0.1%

Remember: We locked down our country, broke the economy and co-erced an experimental product into the arms of our populace for this.